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KMID : 0375920060240010077
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Journal of Rehabilitation Science
2006 Volume.24 No. 1 p.77 ~ p.84
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The Review of Narrow Band UVB Phototherapy in Atopic Dermatitis
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Park Rae-Joon
Park Soo-Kyoung
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Abstract
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Atopic dermatitis is a chronic, inflammatory, primarily genetic-determined skin disease of which the cause is unknown. Its prevalence of has been increased in the industrialized countries, and no one know why. So, atopic eczema remains a therapeutic challenge. There have been no known therapeutic modalities as effective as glucocorticoids for treatment of chronic intractable atopic dermatitis. However, various attempts including phototherapy with UVB irradiation have been tried to avoid side effects from long term corticosteroids treatment. Recently, narrow band ultraviolet B(UVB) phototherapy is introduced and known to be effective in treating atopic dermatitis. It is easier to be applicable because of no need for topical and /or systemic photosensitizers, and comparably or more effectiveness than PUVA without systemic side effects such as vertigo and vomiting. But therapeutic mechanism of narrow band UVB in atopic dermatitis is not yet known exactly. Therefore, a more organized study should be done to discover the therapeutic mechanism of narrow band UVB and determime therapeutic protocol.
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